Differential DNA Methylation in Purified Human Blood Cells
Methylation of cytosines at CpG sites is a common epigenetic DNA modification that can be measured by a large number of methods, now even in a genome-wide manner for hundreds of thousands of sites. The application of DNA methylation analysis is becoming widely popular in complex disorders, for example, to understand part of the “missing inheritance”. The DNA samples most readily available for methylation studies are derived from whole blood. However, blood consists of many functionally and devel...
Provenance — who produced it, who reused it
Linked to 76 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Accounting for cellular heterogeneity is critical in epigenome-w... 2014 · 1,173 cites
- Aging of blood can be tracked by DNA methylation changes at just... 2014 · 955 cites
- Integrative Analysis Identifies Four Molecular and Clinical Subs... 2017 · 914 cites
- HIV-1 Infection Accelerates Age According to the Epigenetic Cloc... 2015 · 597 cites
- DNA methylation loss in late-replicating domains is linked to mi... 2018 · 452 cites
- RnBeads 2.0: comprehensive analysis of DNA methylation data 2019 · 423 cites
- Identification of differentially methylated cell types in epigen... 2018 · 360 cites
- DNA extracted from saliva for methylation studies of psychiatric... 2014 · 358 cites
- Pan-cancer deconvolution of tumour composition using DNA methyla... 2018 · 345 cites
- Sparse PCA corrects for cell type heterogeneity in epigenome-wid... 2016 · 316 cites
- Enhanced cell deconvolution of peripheral blood using DNA methyl... 2022 · 276 cites
- Clinical and Biological Subtypes of B-cell Lymphoma Revealed by... 2021 · 250 cites
- An evaluation of analysis pipelines for DNA methylation profilin... 2013 · 231 cites
- Improving cell mixture deconvolution by identifying optimal DNA... 2016 · 230 cites
- The effect of smoking on DNA methylation of peripheral blood mon... 2014 · 206 cites
- Diagnostic Utility of Genome-wide DNA Methylation Testing in Gen... 2019 · 205 cites
- Identification of DNA Methylation Changes in Newborns Related to... 2014 · 204 cites
- Cell-type-specific resolution epigenetics without the need for c... 2019 · 182 cites
- Genomic DNA Methylation Signatures Enable Concurrent Diagnosis a... 2018 · 179 cites
- DNA methylation–based immune response signature improves patient... 2017 · 156 cites
- Cell-composition effects in the analysis of DNA methylation arra... 2015 · 134 cites
- Gene domain-specific DNA methylation episignatures highlight dis... 2019 · 128 cites
- BAFopathies’ DNA methylation epi-signatures demonstrate diagnost... 2018 · 124 cites
- EPISCORE: cell type deconvolution of bulk tissue DNA methylomes... 2020 · 119 cites
- Genome-wide discovery and validation of diagnostic DNA methylati... 2019 · 115 cites
- Maternal Age at Delivery Is Associated with an Epigenetic Signat... 2016 · 113 cites
- Multilocus loss of DNA methylation in individuals with mutations... 2013 · 107 cites
- MeDeCom: discovery and quantification of latent components of he... 2017 · 105 cites
- TOAST: improving reference-free cell composition estimation by c... 2019 · 105 cites
- An integrated genomics analysis of epigenetic subtypes in human... 2016 · 104 cites
- New targeted approaches for epigenetic age predictions 2020 · 98 cites
- MethylResolver—a method for deconvoluting bulk DNA methylation p... 2020 · 91 cites
- Integration of DNA methylation patterns and genetic variation in... 2019 · 76 cites
42 further papers cite this accession but reuse could not be confirmed.
Deep data QC
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measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently