Impact of miRNAs modulation on regulatory networks and pathways involved in colon cancer and metastasis development
Originally linked with development and differentiation, the role of microRNAs (miRNAs) in many important biological processes has emerged and dysregulation of miRNA expression has been connected with cancer pathogenesis. The association between abnormal expression levels of miRNAs and colon cancer has been mainly demonstrated in primary tumors; more recently, non-overlapping sets of oncomirs, tumour suppressor miRNAs and metastamirs have been associated with distinct stages of colo-rectal can...
Provenance — who produced it, who reused it
Linked to 24 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Knowledge about the presence or absence of miRNA isoforms (isomi... 2017 · 225 cites
- Serum exosomal miR-122 as a potential diagnostic and prognostic... 2019 · 123 cites
- Altered Fecal Small RNA Profiles in Colorectal Cancer Reflect Gu... 2019 · 99 cites
20 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently