Expression data from the Cancer Cell Line Encyclopedia (CCLE)
The Cancer Cell Line Encyclopedia (CCLE) project is a collaboration between the Broad Institute, the Novartis Institutes for Biomedical Research and the Genomics Novartis Foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models It consists of a compilation of gene expression, chromosomal copy number, and massively parallel sequencing data from nearly 1,000 human cancer cell lines. All raw and processed data are available through an integ...
Provenance — who produced it, who reused it
Linked to 65 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- A melanocyte lineage program confers resistance to MAP kinase pa... 2013 · 455 cites
- ZEB1 turns into a transcriptional activator by interacting with... 2016 · 298 cites
- Targeting glutaminase 1 attenuates stemness properties in hepato... 2018 · 239 cites
- Comprehensive comparison of molecular portraits between cell lin... 2016 · 228 cites
- ZIC2-dependent OCT4 activation drives self-renewal of human live... 2015 · 173 cites
- Machine learning-based identification of tumor-infiltrating immu... 2022 · 150 cites
- Liver cancer cell lines distinctly mimic the metabolic gene expr... 2018 · 147 cites
- The mutational landscape of chromatin regulatory factors across... 2013 · 119 cites
- Barasertib (AZD1152), a Small Molecule Aurora B Inhibitor, Inhib... 2016 · 111 cites
- Nitric oxide is a positive regulator of the Warburg effect in ov... 2014 · 84 cites
- 5-hydroxymethylcytosine marks promoters in colon that resist DNA... 2015 · 81 cites
- AKR1C1 controls cisplatin-resistance in head and neck squamous c... 2019 · 74 cites
- Gain-of-Function Genetic Alterations of G9a Drive Oncogenesis 2020 · 73 cites
52 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently