The CURELUNG Project from the Epigenetics Side (Patients dataset)
Non-small cell lung cancer (NSCLC) is a very common solid tumor where only small advances in the reduction of relapse-free survival and overall survival have been accomplished. The issue is particularly critical for stage I patients where there are not available biomarkers, in the absence of detectable nodal or other metastatic involvement, that might indicate which high-risk patients should receive the beneficially proved adjuvant chemotherapy. We aimed to find DNA methylation markers with prog...
Provenance — who produced it, who reused it
Linked to 18 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Epigenomic analysis detects aberrant super-enhancer DNA methylat... 2016 · 221 cites
- Smoking induces coordinated DNA methylation and gene expression... 2018 · 171 cites
- An Integrated Prognostic Classifier for Stage I Lung Adenocarcin... 2015 · 126 cites
- A DNA methylation map of human cancer at single base-pair resolu... 2017 · 102 cites
14 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently