Corpus 1,272 assessed · 1,173 scored · 643 reproduced ≥75 · 168 flagged ·∅ 74.1/100
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GSE39582

GEO first seen 2013

Gene expression Classification of Colon Cancer defines six molecular subtypes with distinct clinical, molecular and survival characteristics [Expression]

Organism
Homo sapiens
Samples
585
Type
Expression profiling by arra...
Submitted
2012-07-23

From a clinical and molecular perspective, colon cancer (CC) is a heterogeneous disease but to date no classification based on high-density transcriptome data has been established. The aim of this study was to build up a robust molecular classification of mRNA expression profiles (Affymetrix U133Plus2) of a large series of 443 CC and 19 non-tumoral colorectal mucosas, and to validate it on an independent serie of 123 CC and 906 public dataset. We identified and validated six molecular subtypes i...

Provenance — who produced it, who reused it

Linked to 410 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
Laetitia MarisaAurélien de ReynièsAlex DuvalJanick SelvesMarie-Pierre GaubLaure VescovoMarie-Christine Etienne-GrimaldiRenaud SchiappaDominique GuenotMira AyadiSylvain KirzinMaurice ChazalJean-François FléjouDaniel BenchimolErwan PencreachArnaud LagardeFrançoise PiardDominique EliasSylviane OlschwangGérard MilanoPierre Laurent-PuigValérie Boige
Gene Expression Classification of Colon Cancer into Molecular Su... 2013
Reused by

32 further papers cite this accession but reuse could not be confirmed.

Deep data QC

metadata only · no data-level QC for this type

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained

No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.

QC cost 4 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently

Scientific quality

Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.

2 studies use it 1 reproduced mean score 70