Purified human leukocyte subtype DNA methylation profiles
The objective of the study was to identify differentially methylated regions of DNA (DMRs) that distinguish human leukocyte subtypes, and hence serve as biomarkers for those immune cell types. This file contains Illumina Infinium HumanMethylation27 BeadChip data for human leukocyte subtypes that were purified from whole blood samples via magnetic activated cell sorting (MACS) and purity confirmed by flourescence activated cell sorting (FACS).
Provenance — who produced it, who reused it
Linked to 10 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- HIV-1 Infection Accelerates Age According to the Epigenetic Cloc... 2015 · 597 cites
- Reference-free cell mixture adjustments in analysis of DNA methy... 2014 · 474 cites
- Many obesity-associated SNPs strongly associate with DNA methyla... 2015 · 193 cites
- DNA methylation–based immune response signature improves patient... 2017 · 156 cites
- Genome-wide age-related DNA methylation changes in blood and oth... 2013 · 135 cites
- Cell-composition effects in the analysis of DNA methylation arra... 2015 · 134 cites
3 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently