HCC Gene Expression Profile
The variability in the prognosis of hepatocellular carcinoma (HCC) patients suggests that HCC may comprise several distinctive biological phenotypes. These phenotypes may result from different neoplastic pathways during the tumorigenesis and/or from a different cell of origin. Here we address if the transcriptional characteristics of the HCC would provide insight into the cellular origin of the tumors. We integrated gene expression data from rat fetal hepatoblasts and adult hepatocytes, HCC from...
Provenance — who produced it, who reused it
Linked to 18 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Keratin 19: a key role player in the invasion of human hepatocel... 2013 · 271 cites
- Sal-like protein 4 (SALL4), a stem cell biomarker in liver cance... 2012 · 195 cites
- Oncogenic Activation of the RNA Binding Protein NELFE and MYC Si... 2017 · 161 cites
- Inactivation of Hippo Pathway Is Significantly Associated with P... 2015 · 124 cites
- The Transcription Factor GLI1 Mediates TGFβ1 Driven EMT in Hepat... 2012 · 76 cites
13 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently