The Genomic Binding Profile of GAGA Element Associated Factor (GAF) in Drosophila S2 cells
GAGA associated transcription factor (GAF) is a highly abundant and essential protein in Drosophila. GAF recognizes and binds arrays of GA dinucleotides via a zinc finger DNA binding domain to regulate transcription by binding to general TF machinery or recruit nucleosome remodeling factors. We performed GAF ChIP-seq to quantify the intensity of GAF binding at high resolution in S2 cells. In addition, we performed GAF ChIP-seq in S2 cells that were depleted of GAF by RNAi. By quantifying the deg...
Provenance — who produced it, who reused it
Linked to 5 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- GAF is essential for zygotic genome activation and chromatin acc... 2021 · 153 cites
- GAGA Factor Maintains Nucleosome-Free Regions and Has a Role in... 2015 · 117 cites
- CBP Regulates Recruitment and Release of Promoter-Proximal RNA P... 2017 · 97 cites
- Many chronological aging clocks can be found throughout the epig... 2021 · 71 cites
1 further paper cites this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently