Airway Epithelial Gene Expression Diagnostic for the Evaluation of Smokers with Suspect Lung Cancer
RNA was obtained from histologically normal bronchial epithelium of smokers during time of clinical bronchoscopy from relatively accessible airway tissue. Gene expression data from smokers with lung cancer was compared with samples from smokers without lung cancer. This allowed us to generate a diagnostic gene expression profile that could distinguish the two classes. This profile could provide additional clinical benefit in diagnosing cancer amongst smokers with suspect lung cancer.
Provenance — who produced it, who reused it
Linked to 18 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Dissection of Regulatory Networks that Are Altered in Disease vi... 2013 · 182 cites
- Identifying dysregulated pathways in cancers from pathway intera... 2012 · 126 cites
- Alternative empirical Bayes models for adjusting for batch effec... 2018 · 122 cites
- Differential regulation of the REGγ–proteasome pathway by p53/TG... 2013 · 104 cites
14 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently