Inflammation, adenoma and cancer: objective classification of colon biopsy specimens with gene expression signature
Background and Aims: Gene expression analysis of colon biopsies using high-density oligonucleotide microarray can contribute to the understanding of local pathophysiological alterations and to functional classification of precancerous adenoma, different stage colorectal carcinomas (CRC) and inflammatory bowel diseases (IBD). Results: Significant overexpression of collagen IV, lipocalin-2, caveolin-1, calumenin genes, and significant dowregulation of aquaporin-8, amnionless homolog, prostaglandi...
Provenance — who produced it, who reused it
Linked to 64 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Oncostatin M drives intestinal inflammation and predicts respons... 2017 · 798 cites
- A molecular mechanism that links Hippo signalling to the inhibit... 2012 · 375 cites
- Differential regulation of the REGγ–proteasome pathway by p53/TG... 2013 · 104 cites
- Mass cytometry reveals systemic and local immune signatures that... 2019 · 96 cites
- Comparative study on gene set and pathway topology-based enrichm... 2015 · 91 cites
- Long noncoding RNA LINC02418 regulates MELK expression by acting... 2019 · 90 cites
- Removing batch effects for prediction problems with frozen surro... 2014 · 88 cites
- A distinct p53 target gene set predicts for response to the sele... 2015 · 87 cites
- Targeting nonsense-mediated mRNA decay in colorectal cancers wit... 2018 · 83 cites
- An integrative analysis reveals functional targets of GATA6 tran... 2013 · 81 cites
- Ranking metrics in gene set enrichment analysis: do they matter? 2017 · 80 cites
- Aging related methylation influences the gene expression of key... 2016 · 78 cites
52 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently