Molecular subclasses of high-grade glioma: prognosis, disease progression, and neurogenesis
Novel prognostic subclasses of high-grade astrocytoma are identified and discovered to resemble stages in neurogenesis. One tumor class displaying neuronal lineage markers shows longer survival, while two tumor classes enriched for neural stem cell markers display equally short survival. Poor prognosis subclasses exhibit either markers of proliferation or of angiogenesis and mesenchyme. Analysis of gene expression data is described in Phillips et al., Cancer Cell, 2006.
Provenance — who produced it, who reused it
Linked to 57 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Contribution of serine, folate and glycine metabolism to the ATP... 2013 · 265 cites
- EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Deat... 2015 · 175 cites
- Fibulin-3 Promotes Glioma Growth and Resistance through a Novel... 2012 · 91 cites
- Induction of the Unfolded Protein Response Drives Enhanced Metab... 2013 · 72 cites
53 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently