Hierarchical mechanisms for transcription factor-mediated reprogramming of fibroblasts to neurons
Here we reveal a hierarchical mechanism in the direct conversion of fibroblasts into induced neuronal (iN) cells mediated by the transcription factors Ascl1, Brn2, and Myt1l.
Provenance — who produced it, who reused it
Linked to 13 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Structural Features of Transcription Factors Associating with Nu... 2019 · 226 cites
- Ascl1 Coordinately Regulates Gene Expression and the Chromatin L... 2015 · 198 cites
- Proneural factors Ascl1 and Neurog2 contribute to neuronal subty... 2019 · 150 cites
- The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in huma... 2019 · 78 cites
- Many chronological aging clocks can be found throughout the epig... 2021 · 71 cites
7 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently