Alzheimer's Disease Dataset
This dataset contains microarray data from normal controls (aged 20-99 yrs) and Alzheimer's disease cases, from 4 brain regions: hippocampus, entorhinal cortex, superior frontal cortex, post-central gyrus. Changes in expression of synaptic and immune related genes were analyzed, investigating age-related changes and AD-related changes, and region-specific patterns of change. These AD cases were processed simultaneously with the control cases (young and aged) included in GSE11882 (GSE11882 dat...
Provenance — who produced it, who reused it
Linked to 87 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Dysregulation of multiple metabolic networks related to brain tr... 2020 · 163 cites
- Abnormal brain cholesterol homeostasis in Alzheimer’s disease—a... 2021 · 152 cites
- Interpretable deep learning translation of GWAS and multi-omics... 2022 · 103 cites
- Divergent roles of astrocytic versus neuronal EAAT2 deficiency o... 2019 · 96 cites
- Alzheimer’s disease master regulators analysis: search for poten... 2018 · 95 cites
- AlzGPS: a genome-wide positioning systems platform to catalyze m... 2021 · 88 cites
- Integrative genomics approach identifies conserved transcriptomi... 2020 · 83 cites
- Arid1b Haploinsufficiency Causes Abnormal Brain Gene Expression... 2017 · 79 cites
- Identification of age- and gender-associated long noncoding RNAs... 2019 · 79 cites
- Integrated multi-omics analysis of Alzheimer’s disease shows mol... 2023 · 77 cites
70 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently
Scientific quality
Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.