Human liver biopsy of different phases from control to NASH
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in industrialized countries. Liver samples from morbidly obese patients (N=45) with all stages of NAFLD and controls (N=18) were analysed by array-based DNA methylation and mRNA expression profiling. NAFLD-specific expression and methylation differences were seen for nine genes coding for key enzymes in intermediate metabolism (including PC, ACLY, PLCG1) and insulin/insulin-like signalling (including IGF1, IGFBP2...
Provenance — who produced it, who reused it
Linked to 71 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Yes‐Associated Protein in Kupffer Cells Enhances the Production... 2019 · 104 cites
- Spermidine-mediated hypusination of translation factor EIF5A imp... 2022 · 88 cites
- S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy an... 2020 · 86 cites
- miR-135b Stimulates Osteosarcoma Recurrence and Lung Metastasis... 2017 · 75 cites
67 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently