Expression data for Nonalcoholic fatty liver disease patients
Nonalcoholic fatty liver disease represents a spectrum of pathology that ranges from benign steatosis to potentially-progressive steatohepatitis and affects more than 30% of US adults. Advanced NAFLD is associated with increased morbidity and mortality from cirrhosis, primary liver cancer, cardiovascular disease and extrahepatic cancers. Accurate identification of patients at risk for advanced NAFLD is challenging. The aims of this study were to define the liver gene expression patterns that di...
Provenance — who produced it, who reused it
Linked to 30 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Autophagy is a gatekeeper of hepatic differentiation and carcino... 2018 · 164 cites
- The XBP1 Arm of the Unfolded Protein Response Induces Fibrogenic... 2016 · 101 cites
- Targeting clinical epigenetic reprogramming for chemoprevention... 2020 · 95 cites
- AKR1D1 is a novel regulator of metabolic phenotype in human hepa... 2019 · 88 cites
- Spermidine-mediated hypusination of translation factor EIF5A imp... 2022 · 88 cites
- S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy an... 2020 · 86 cites
- Characterization of transcriptional modules related to fibrosing... 2017 · 75 cites
23 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently
Scientific quality
Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.