Corpus 1,272 assessed · 1,173 scored · 643 reproduced ≥75 · 168 flagged ·∅ 74.1/100
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GSE50660

GEO first seen 2014

Cigarette Smoking Reduces DNA Methylation Levels at Multiple Genomic Loci but the Effect is Partially Reversible upon Cessation

Organism
Homo sapiens
Samples
464
Type
Methylation profiling by arr...
Submitted
2013-09-06

DNA methylation is an epigenetic event whose pattern is altered frequently in a wide variety of human diseases. Smoking affects DNA methylation possibly leading to abnormal expression of a broad spectrum of genes which in turn may result to the various side effects and diseases associated with smoking. The long term effects of smoking have been widely studied but the mechanism(s) by which those effects may be reversible by smoking cessation are not clearly understood. Here, we conducted an epige...

Provenance — who produced it, who reused it

Linked to 13 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
Loukia G TsaprouniT P YangJordana T BellKatherine J DickStavroula KanoniJames NisbetAna ViñuelaElin GrundbergChristopher P NelsonEshwar MeduriAlfonso BuilFrancois CambienChristian HengstenbergJeanette ErdmannHeribert SchunkertAlison H GoodallWillem H OuwehandEmmanouil T DermitzakisTim D SpectorNilesh J SamaniPanos Deloukas
Reused by

8 further papers cite this accession but reuse could not be confirmed.

Deep data QC

metadata only · no data-level QC for this type

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained

Data type / assay
methylation
Organism
Homo sapiens
Files available
TXT
Metrics (value · how obtained)
supplementary file types TXT reported
QC cost 5 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently