A signature predicting poor prognosis in gastric and ovarian cancer represents a coordinated macrophage and stromal-response.
Genome wide mRNA expression profiling of 94 gastric tumours derived from Australian based cohort was performed. . From this data we identified a cluster of co-expressed genes termed the stromal response cluster which almost perfectly differentiates tumor from its non-malignant gastric tissue and hence can be regarded as a highly tumor-specific gene expression signature. We show that these genes are consistently co-expressed across a range of independent gastric datasets as well as other cancer...
Provenance — who produced it, who reused it
Linked to 46 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- CD36 mediates palmitate acid-induced metastasis of gastric cance... 2019 · 222 cites
- Stearoyl-CoA desaturase 1 (SCD1) facilitates the growth and anti... 2020 · 148 cites
- LncRNA MAGI2-AS3 Is Regulated by BRD4 and Promotes Gastric Cance... 2019 · 142 cites
- Lysyl oxidase promotes liver metastasis of gastric cancer via fa... 2019 · 114 cites
- <i>Helicobacter pylori</i> ‐induced miR‐135b‐5p promotes cisplat... 2018 · 109 cites
- TEAD1/4 exerts oncogenic role and is negatively regulated by miR... 2017 · 93 cites
- PODXL, negatively regulated by KLF4, promotes the EMT and metast... 2018 · 90 cites
- N6-methyladenosine-dependent pri-miR-17-92 maturation suppresses... 2020 · 81 cites
- The m6A Reader YTHDF1 Facilitates the Tumorigenesis and Metastas... 2021 · 81 cites
- Histone methyltransferase SETD1A interacts with HIF1α to enhance... 2020 · 76 cites
36 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently