Epigenome analysis of human epidermal and dermal samples with aging and sun exposure
Genome wide DNA methylation profiling of epidermal and dermal samples obtained from sun-exposed and sun-protected body sites from younger (<35 years old) and older (>60 years old) individuals. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 450,000 CpGs in dermal and epidermal samples. Samples included 10 younger sun protected dermal samples, 10 younger sun exposed dermal samples, 10 older sun protected dermal samples, 1...
Provenance — who produced it, who reused it
Linked to 10 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- DNA methylation loss in late-replicating domains is linked to mi... 2018 · 452 cites
- Age-related accrual of methylomic variability is linked to funda... 2016 · 197 cites
- Causality-enriched epigenetic age uncouples damage and adaptatio... 2024 · 179 cites
- A comparison of epigenetic mitotic-like clocks for cancer risk p... 2020 · 153 cites
- DNA Methylation Patterns Separate Senescence from Transformation... 2018 · 122 cites
- A pan-tissue DNA methylation atlas enables in silico decompositi... 2022 · 107 cites
- A suite of DNA methylation markers that can detect most common h... 2017 · 72 cites
3 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently