Large-scale deployment of embryonic gene programming in human and murine colon cancer: a new target for intervention.
Goal of the experiment: To identify and understand the overall transcriptional programming of human colorectal cancer tumors by evaluating gene expression profiles of tumors from four murine models, and comparing and contrasting these to the developing stages of the mouse embryonic colon. Experiment description: Colorectal cancer results from multiple genetic and epigenetic events that produce variable histologies and clinical outcomes. To identify gene regulatory programs that underlie colon tu...
Provenance — who produced it, who reused it
Linked to 23 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Exosomal MALAT1 sponges miR-26a/26b to promote the invasion and... 2020 · 162 cites
- The POU2F1-ALDOA axis promotes the proliferation and chemoresist... 2022 · 138 cites
- FOXKs Promote Wnt/β-Catenin Signaling by Translocating DVL into... 2015 · 137 cites
- Notch1 counteracts WNT/β-catenin signaling through chromatin mod... 2012 · 133 cites
- ILF3 is a substrate of SPOP for regulating serine biosynthesis i... 2019 · 106 cites
- TMEM9 promotes intestinal tumorigenesis through vacuolar-ATPase-... 2018 · 94 cites
- The lncRNA ZFAS1 regulates lipogenesis in colorectal cancer by b... 2021 · 76 cites
16 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently