Large hypomethylated blocks related to large heterochromatin regions as a universal defining epigenetic alteration in human solid tumors
Examined methylation status using HumanMethylation450 BeadChip for samples from 5 different tissue of normal, hyperplastic, adenoma, cancer and metastatic samples.
Provenance — who produced it, who reused it
Linked to 12 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Age-related DNA methylation changes are tissue-specific with ELO... 2018 · 227 cites
- Bacteria pathogens drive host colonic epithelial cell promoter h... 2020 · 146 cites
9 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently