Temporal gene expression across osteoblastogenesis.
Purpose: Osteoblast cells mature from a mesenchymal stem cell pool to become cells capable of forming bone matrix and mineralizing this matrix. The goal of this study was to characterize temporal changes in the transcriptome across osteoblast maturation, starting with committed mesenchymal stem cell/ early pre-osteoblast stage through to mature osteoblasts capable of matrix mineralization. Methods: Enriched populations of pre-osteoblast like cells were obtained from neonatal calvaria from C57B...
Provenance — who produced it, who reused it
Linked to 12 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Identification of 153 new loci associated with heel bone mineral... 2017 · 517 cites
- Phenotypic Dissection of Bone Mineral Density Reveals Skeletal S... 2014 · 168 cites
- Monoallelic IFT140 pathogenic variants are an important cause of... 2021 · 165 cites
- Integrating GWAS and Co-expression Network Data Identifies Bone... 2016 · 123 cites
8 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently