Core Ileal Transcriptome in Pediatric Crohn Disease
We report the global pattern of ileal gene expression in a cohort of 359 treatment-naïve pediatric Crohn Disease, Ulcerative Colitis patients and controls. We focus on genes with consistent altered expression in inflamed and unaffected ileum of CD [ileal-involved CD (iCD) and non-invloved ileal CD (cCD)], but not in the ileum of ulcerative colitis or control.
Provenance — who produced it, who reused it
Linked to 24 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Oncostatin M drives intestinal inflammation and predicts respons... 2017 · 798 cites
- IL-1-driven stromal–neutrophil interactions define a subset of p... 2021 · 289 cites
- Gut-innervating nociceptors regulate the intestinal microbiota t... 2022 · 166 cites
- IL-7 receptor influences anti-TNF responsiveness and T cell gut... 2019 · 132 cites
19 further papers cite this accession but reuse could not be confirmed.
Deep data QC
95/100 · AStandardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured
The A grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0