Phase II exploratory pharmacogenomics study of cetuximab monotherapy in patients with advanced metastatic CRC
Patients with metastatic colorectal cancer were enrolled for treatment with cetuximab monotherapy. Transcriptional profiling was conducted on RNA from pre-treatment metastatic site biopsies to identify genes whose expression correlates with best clinical responses.
Provenance — who produced it, who reused it
Linked to 15 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Significant Association of Oncogene YAP1 with Poor Prognosis and... 2014 · 162 cites
- Unequal prognostic potentials of p53 gain-of-function mutations... 2014 · 97 cites
- Metastasis-associated PRL-3 induces EGFR activation and addictio... 2013 · 85 cites
12 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently