Human liver gene expression data from subjects of varying ages
N=134 human liver samples from morbidly obese patients and healthy controls were analysed by array-based mRNA expression profiling. Liver messenger RNA expression datasets from the German patients were generated on the HuGene 1.1 ST gene array The purpose of the study was to correlate these gene expression data with body mass index and with an epigenetic measure of age acceleration based on DNA methylation data.
Provenance — who produced it, who reused it
Linked to 16 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Obesity accelerates epigenetic aging of human liver 2014 · 817 cites
- Remodeling of epigenome and transcriptome landscapes with aging... 2019 · 373 cites
- Yes‐Associated Protein in Kupffer Cells Enhances the Production... 2019 · 104 cites
- The XBP1 Arm of the Unfolded Protein Response Induces Fibrogenic... 2016 · 101 cites
12 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently