Large-scale gene expression profiling of 81 hepatocellular carcinomas
Hepatocellular carcinoma (HCC) is ranked second in cancer-associated deaths worldwide. Most cases of HCC are secondary to either a viral hepatitis infection (hepatitis B or C) or cirrhosis (alcoholism being the most common cause of hepatic cirrhosis). It is a complex and heterogeneous tumor due to activation of multiple cellular pathways and molecular alterations.
Provenance — who produced it, who reused it
Linked to 86 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Exome sequencing of hepatocellular carcinomas identifies new mut... 2015 · 1,850 cites
- Identification of the Consistently Altered Metabolic Targets in... 2017 · 156 cites
- Establishment and validation of a cholesterol metabolism-related... 2022 · 139 cites
- <scp>FAM</scp>83 family oncogenes are broadly involved in human... 2017 · 128 cites
- CCT3 acts upstream of YAP and TFCP2 as a potential target and tu... 2019 · 118 cites
- Lysyl Oxidase‐Like 4 Fosters an Immunosuppressive Microenvironme... 2020 · 113 cites
- RBM15 promotes hepatocellular carcinoma progression by regulatin... 2021 · 111 cites
- Early Diagnosis of Hepatocellular Carcinoma Using Machine Learni... 2020 · 97 cites
- MiR-126 negatively regulates PLK-4 to impact the development of... 2018 · 86 cites
- DNA topoisomerase 1 and 2A function as oncogenes in liver cancer... 2018 · 83 cites
70 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently