Gene expression in Stage 1,2 Normal and Tumor kidney cancer
Although renal cell carcinoma (RCC) is the sixth-leading cause of cancer death, the molecular events leading to disease onset and progression are not well understood. Genomic profiling of clear cell RCC (cRCC) patients indicated that loss of a negative regulator of the Wnt pathway, secreted frizzled-related protein 1 (sFRP1), occurred in the majority of more than 100 patients tested. To our knowledge, this is the first report of loss of sFRP1 expression in patients diagnosed with cRCC; this loss...
Provenance — who produced it, who reused it
Linked to 44 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Suppression of PGC-1α Is Critical for Reprogramming Oxidative Me... 2015 · 188 cites
- Gene set enrichment for reproducible science: comparison of CERN... 2019 · 136 cites
- The effect of carbonic anhydrase IX on focal contacts during cel... 2013 · 96 cites
- MiR-532-5p suppresses renal cancer cell proliferation by disrupt... 2018 · 83 cites
- Ranking metrics in gene set enrichment analysis: do they matter? 2017 · 80 cites
- DACH1 inhibits cyclin D1 expression, cellular proliferation and... 2014 · 71 cites
- Epithelial tumor suppressor ELF3 is a lineage-specific amplified... 2019 · 71 cites
37 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently