Single-nucleotide resolution mapping of m6A and m6Am throughout the transcriptome
N6-methyladenosine (m6A) is the most abundant modified base in eukaryotic mRNA and has been linked to diverse effects on mRNA fate and function. Current m6A mapping approaches rely on immunoprecipitation of m6A-containing RNA fragments to identify regions of transcripts that contain m6A. This approach localizes m6A residues to 100-200 nt-long regions of transcripts. The precise position of m6A in mRNAs cannot be identified on a transcriptome-wide level because there are no chemical methods to...
Provenance — who produced it, who reused it
Linked to 15 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- m6A RNA methylation promotes XIST-mediated transcriptional repre... 2016 · 1,794 cites
- A Unified Model for the Function of YTHDF Proteins in Regulating... 2020 · 855 cites
- R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia b... 2021 · 345 cites
- METTL3 promotes tumour development by decreasing APC expression... 2021 · 193 cites
- RNA–protein interaction mapping via MS2- or Cas13-based APEX tar... 2020 · 168 cites
- Attention-based multi-label neural networks for integrated predi... 2021 · 134 cites
- Structural modularity of the XIST ribonucleoprotein complex 2020 · 97 cites
6 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently