Single-cell chromatin accessibility data using scATAC-seq
Cell-to-cell variation is a universal feature of life that impacts a wide range of biological phenomena, from developmental plasticity to tumor heterogeneity. While recent advances have improved our ability to document cellular phenotypic variation the fundamental mechanisms that generate variability from identical DNA sequences remain elusive. Here we reveal the landscape and principles of cellular DNA regulatory variation by developing a robust method for mapping the accessible genome of indiv...
Provenance — who produced it, who reused it
Linked to 26 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Lineage-specific and single-cell chromatin accessibility charts... 2016 · 1,292 cites
- Chromatin Potential Identified by Shared Single-Cell Profiling o... 2020 · 1,205 cites
- High-throughput sequencing of the transcriptome and chromatin ac... 2019 · 891 cites
- Identification of transcription factor binding sites using ATAC-... 2019 · 510 cites
- Integrative analyses of single-cell transcriptome and regulome u... 2020 · 215 cites
- Profiling of Pluripotency Factors in Single Cells and Early Embr... 2019 · 209 cites
- Enhancer viruses for combinatorial cell-subclass-specific labeli... 2021 · 207 cites
- Single-cell lineage tracing by endogenous mutations enriched in... 2019 · 148 cites
- Chromatin-accessibility estimation from single-cell ATAC-seq dat... 2021 · 132 cites
- Simultaneous deep generative modelling and clustering of single-... 2021 · 118 cites
- Classifying cells with Scasat, a single-cell ATAC-seq analysis t... 2018 · 82 cites
- Parallel bimodal single-cell sequencing of transcriptome and chr... 2020 · 73 cites
13 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently