Genome-wide gene expression differences between Crohn’s and ulcerative colitis from endoscopic pinch biopsies:
Ulcerative colitis (UC) and Crohn’s disease (CD) are inflammatory bowel diseases (IBD) with variable, overlapping clinical features and complex pathophysiologies. To identify pathogenic processes underlying these disease subtypes, using single endoscopic pinch biopsies to estabolish 36 expression profiles, we elucidated gene expression patterns of active and inactive areas of UC and CD, and compared these to infectious colitis and healthy controls.
Provenance — who produced it, who reused it
Linked to 18 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Dissecting direct reprogramming from fibroblast to neuron using... 2016 · 493 cites
- The NLRP1 Inflammasome Attenuates Colitis and Colitis-Associated... 2015 · 163 cites
- Artificial intelligence guided discovery of a barrier-protective... 2021 · 82 cites
- Highly interconnected genes in disease-specific networks are enr... 2012 · 81 cites
14 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently