Corpus 1,272 assessed · 1,173 scored · 643 reproduced ≥75 · 168 flagged ·∅ 74.1/100
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GSE68762

GEO first seen 2016

Bacteria differently regulate mRNA abundance to specifically respond to various stresses

Organism
Escherichia coli str. K-12 substr. MC4100
Samples
10
Type
Expression profiling by high...
Submitted
2015-05-11

Environmental stress is detrimental to cell viability and requires an adequate reprogramming of cellular activities to maximize cell survival. We present a global analysis of the response of Escherichia coli to acute heat and osmotic stress. We combine deep sequencing of total mRNA and ribosome-protected fragments to provide a genome-wide map of the stress response at transcriptional and translational level. For each type of stress, we observe a unique subset of genes that shape the stress-speci...

Provenance — who produced it, who reused it

Linked to 5 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
Alexander BartholomäusIvan FedyuninPeter FeistCeline SinGong ZhangAngelo VallerianiZoya Ignatova
Reused by

3 further papers cite this accession but reuse could not be confirmed.

Deep data QC

metadata only · no data-level QC for this type

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained

Data type / assay
bulk-RNA-seq
Organism
Escherichia coli str. K-12 substr. MC4100
Instrument
Illumina Genome Analyzer IIx
Platform
ILLUMINA
Read type
short-read
Files available
FASTQ (raw reads)
N numbers (samples, groups)
10 / 10 runs
Completeness
100%
Metrics (value · how obtained)
checksum ok yes reported
total bases 11890713492 reported
total reads 330297597 reported
supplementary file types TXT reported
QC cost 11 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently