Single-cell RNA sequencing of lung adenocarcinoma patient-derived cells
To address how intratumoral heterogeneity affects anti-cancer drug responses, we profiled transcriptomes of single cancer cells originating from lung adenocarcinoma patient-derived xenograft (PDX) tumors.
Provenance — who produced it, who reused it
Linked to 13 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Single-cell mRNA sequencing identifies subclonal heterogeneity i... 2015 · 287 cites
- Integration of single-cell RNA-seq data into population models t... 2019 · 122 cites
- Using single nucleotide variations in single-cell RNA-seq to ide... 2018 · 88 cites
- Single-cell RNA sequencing of lung adenocarcinoma reveals hetero... 2019 · 79 cites
- Measuring intratumor heterogeneity by network entropy using RNA-... 2016 · 77 cites
8 further papers cite this accession but reuse could not be confirmed.
Deep data QC
100/100 · AStandardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured
The A grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0