DNA Methylation of African Americans from the Grady Trauma Project
Childhood and cumulative exposure to trauma increases an individual's lifetime risk for psychiatric and stress-related disorders. This study evaluates DNA methylation in whole blood from African American participants, with the goal of identifying associaitons between peripheral DNA methylation and psychiatric symptoms.
Provenance — who produced it, who reused it
Linked to 15 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Lifetime stress accelerates epigenetic aging in an urban, Africa... 2015 · 479 cites
- Genome-wide association studies identify 137 genetic loci for DN... 2021 · 303 cites
- Estimation of a significance threshold for epigenome‐wide associ... 2017 · 206 cites
- Aging clocks based on accumulating stochastic variation 2024 · 112 cites
- DNA methylation age is accelerated in alcohol dependence 2018 · 103 cites
- Methylomic profiling and replication implicates deregulation of... 2017 · 84 cites
9 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently