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The effect of vedolizumab (anti-α4β7-integrin) therapy on colonic mucosal gene expression in patients with ulcerative colitis (UC)
Microarrays were used to investigate the the effect of vedolizumab (VDZ) therapy on colonic mucosal gene expression in UC patients and compared the changes to those observed with infliximab (IFX) therapy.
Provenance — who produced it, who reused it
Linked to 31 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
Deposited / produced by
Ingrid ArijsGert De HertoghLeentje Van LommelFrans SchuitGert Van AsschePaul RutgeertsSeverine Vermeire
Reused by
- IL-1-driven stromal–neutrophil interactions define a subset of p... 2021 · 289 cites
- Conserved transcriptomic profile between mouse and human colitis... 2019 · 134 cites
- IL-7 receptor influences anti-TNF responsiveness and T cell gut... 2019 · 132 cites
- Single-Cell Transcriptional Survey of Ileal-Anal Pouch Immune Ce... 2021 · 86 cites
- Artificial intelligence guided discovery of a barrier-protective... 2021 · 82 cites
26 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
Data type / assay
microarray-expr
Organism
Homo sapiens
Read type
not sequencing
Files available
CEL
Metrics (value · how obtained)
supplementary file types
CEL
reported
QC cost
1 s compute
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently