Gene Expression Patterns Involved in the Malignant Transformation and Progression of Metastatic Melanoma
Metastatic melanoma is a deadly disease while non-metastatic melanoma and other cutaneous tumor types are usually cured with surgical removal of the primary tumors. This study evaluated gene expresion to determine if gene expression differences existed which would allow one to identify the metastatic tumors based on the expression of specific genes.
Provenance — who produced it, who reused it
Linked to 60 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- PGC1α Expression Defines a Subset of Human Melanoma Tumors with... 2013 · 703 cites
- A Systems Biology Approach Identifies FUT8 as a Driver of Melano... 2017 · 313 cites
- The Immune Microenvironment Confers Resistance to MAPK Pathway I... 2014 · 209 cites
- Diverse matrix metalloproteinase functions regulate cancer amoeb... 2014 · 196 cites
- Regional Activation of Myosin II in Cancer Cells Drives Tumor Pr... 2019 · 173 cites
- Downregulation of RNF128 activates Wnt/β-catenin signaling to in... 2019 · 173 cites
- FBXW7 modulates cellular stress response and metastatic potentia... 2015 · 156 cites
- Co-clinical assessment identifies patterns of BRAF inhibitor res... 2015 · 131 cites
- NLRP1 promotes tumor growth by enhancing inflammasome activation... 2017 · 124 cites
- Histone lactylation-boosted ALKBH3 potentiates tumor progression... 2023 · 115 cites
- Notch3 Functions as a Tumor Suppressor by Controlling Cellular S... 2013 · 108 cites
- Comprehensive DNA methylation study identifies novel progression... 2017 · 99 cites
- ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and... 2020 · 89 cites
- A distinct p53 target gene set predicts for response to the sele... 2015 · 87 cites
- Signaling pathways activation profiles make better markers of ca... 2014 · 79 cites
- Loss of GCNT2/I-branched glycans enhances melanoma growth and su... 2018 · 79 cites
44 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently