Functional interactors of genomewide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue
Multiple gene expression studies have been performed in lung or airway tissues from subjects with chronic obstructive pulmonary disease (COPD). However, in comparison to genome-wide association studies (GWAS), there has been poor replication across these studies. We sought to perform gene expression profiling on a large sample of severe COPD cases and control smokers and use network methods to identify interacting genes and pathways. We collected surgically-resected lung tissue samples from subj...
Provenance — who produced it, who reused it
Linked to 36 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- The arginine methyltransferase PRMT7 promotes extravasation of m... 2022 · 128 cites
- Functional interactors of three genome-wide association study ge... 2017 · 113 cites
- Gene co-expression in the interactome: moving from correlation t... 2021 · 92 cites
33 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently