RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes in Human Normal and Cancerous Tissues
Circular RNAs (circRNAs) represent a novel class of widespread and diverse endogenous RNAs that may regulate gene expression in eukaryotes. However, the regulation and function of human circRNAs remain largely unknown. Here we generate ribosomal-depleted RNA sequencing data from six normal tissues and seven cancers, and detect at least 27,000 circRNA candidates.
Provenance — who produced it, who reused it
Linked to 12 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Circular RNA circRHOBTB3 acts as a sponge for miR-654-3p inhibit... 2020 · 269 cites
- Targeting the circBMPR2/miR-553/USP4 Axis as a Potent Therapeuti... 2019 · 99 cites
- <p>Circular RNA hsa_circ_0072309 inhibits proliferation an... 2019 · 83 cites
- circEHBP1 promotes lymphangiogenesis and lymphatic metastasis of... 2021 · 83 cites
- Aberrant Nuclear Export of circNCOR1 Underlies SMAD7-Mediated Ly... 2022 · 73 cites
6 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently