Stress-induced accumulation of DNA N6-Methyladenine in prefrontal cortex
Chemical covalent modifications on the 5-carbon position of cytosine, such as 5- methylcytosine and 5-hydroxymethylcytosine, are a set of well-characterized epigenetic marks that shape transcriptional landscaping. Compiling evidence suggests central roles of cytosine modification dynamics in neuronal functions such as memory formation and stress response. N6-methyladenine (6mA) that previously described in bacteria has been recently found in higher eukaryotes, including worms, flies and mice. Ho...
Provenance — who produced it, who reused it
Linked to 2 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- DNA N6-methyladenine is dynamically regulated in the mouse brain... 2017 · 215 cites
- A reassessment of DNA-immunoprecipitation-based genomic profilin... 2018 · 110 cites
Deep data QC
72/100 · CStandardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured
The C grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0