A single-cell transcriptome atlas of the human pancreas
To understand organ (dys)function it is important to have a complete inventory of its cell types and the corresponding markers that unambiguously identify these cell types. This is a challenging task, in particular in human tissues, because unique cell-type markers are typically unavailable, necessitating the analysis of complex cell type mixtures. Transcriptome-wide studies on pancreatic tissue are typically done on pooled islet material. To overcome this challenge we sequenced the transcriptom...
Provenance — who produced it, who reused it
Linked to 17 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Comprehensive Integration of Single-Cell Data 2019 · 16,818 cites
- Integrating single-cell transcriptomic data across different con... 2018 · 14,641 cites
- Batch effects in single-cell RNA-sequencing data are corrected b... 2018 · 2,713 cites
- Benchmarking atlas-level data integration in single-cell genomic... 2021 · 1,404 cites
- Efficient integration of heterogeneous single-cell transcriptome... 2019 · 997 cites
- Iterative transfer learning with neural network for clustering a... 2020 · 156 cites
- scAlign: a tool for alignment, integration, and rare cell identi... 2019 · 111 cites
- De novo analysis of bulk RNA-seq data at spatially resolved sing... 2022 · 95 cites
- Learning interpretable cellular and gene signature embeddings fr... 2021 · 94 cites
- PyMINEr Finds Gene and Autocrine-Paracrine Networks from Human I... 2019 · 80 cites
6 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently