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The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-Resistant, sensitive and healthy control
To identify the potential genes/signaling pathways related to R-2HG sensitivity in leukemia cells.
Provenance — who produced it, who reused it
Linked to 2 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
Deposited / produced by
Jianjun ChenRui SuLei Dong
Reused by
- R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia b... 2021 · 345 cites
Deep data QC
100/100 · AStandardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured
Data type / assay
bulk-RNA-seq
Organism
Homo sapiens
Metrics (value · how obtained)
n content pct
0.035
measured
pct q20 bases
96.5
measured
pct q30 bases
94
measured
gc content pct
42.9
measured
mean read length
51
measured
mean base quality
37.3
measured
adapter content pct
0.36
measured
duplication rate pct
29.87
measured
How this grade was computed
Weighted mean of 4 scored metric(s) → 100/100
The A grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.
pct q30 bases
94
measured
×1
100%
mean base quality
37.3
measured
×0.6
100%
adapter content pct
0.36
measured
×0.4
100%
duplication rate pct
29.87
measured
×0.4
100%
QC cost
26 s compute
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0