Expression data from healthy controls and early stage CRC patient's tumor
Metastasis is the major cause of cancer mortality. Up to 25% of early stage sporadic colorectal cancer (CRC) patients succumb to metastasis after curative surgery. We used microarrays to detail gene expression and identified a metastasis-prone signature for early stage CRC.
Provenance — who produced it, who reused it
Linked to 98 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- m6A-induced lncRNA RP11 triggers the dissemination of colorectal... 2019 · 453 cites
- METTL14-mediated N6-methyladenosine modification of SOX4 mRNA in... 2020 · 447 cites
- LncRNA SATB2-AS1 inhibits tumor metastasis and affects the tumor... 2019 · 338 cites
- The long noncoding RNA SNHG1 regulates colorectal cancer cell gr... 2018 · 322 cites
- lncRNA SNHG6 regulates EZH2 expression by sponging miR-26a/b and... 2019 · 244 cites
- RETRACTED ARTICLE: YAP1-induced MALAT1 promotes epithelial–mesen... 2018 · 214 cites
- Targeting YAP1/LINC00152/FSCN1 Signaling Axis Prevents the Progr... 2019 · 166 cites
- N6-methyladenosine-induced circ1662 promotes metastasis of color... 2021 · 165 cites
- Down-weighting overlapping genes improves gene set analysis 2012 · 162 cites
- Downregulation of MEIS1 mediated by ELFN1-AS1/EZH2/DNMT3a axis p... 2022 · 151 cites
- USP11 promotes growth and metastasis of colorectal cancer via PP... 2019 · 139 cites
- The POU2F1-ALDOA axis promotes the proliferation and chemoresist... 2022 · 138 cites
- ILF3 is a substrate of SPOP for regulating serine biosynthesis i... 2019 · 106 cites
- Comprehensive investigation of a novel differentially expressed... 2017 · 100 cites
- Comparative study on gene set and pathway topology-based enrichm... 2015 · 91 cites
- Long noncoding RNA LINC02418 regulates MELK expression by acting... 2019 · 90 cites
- TRIP13 promotes tumor growth and is associated with poor prognos... 2018 · 89 cites
- Long non‐coding <scp>RNA FOXP</scp>4‐<scp>AS</scp>1 is an unfavo... 2016 · 87 cites
- The Histone Acetyltransferase GCN5 Expression Is Elevated and Re... 2015 · 84 cites
- Highly interconnected genes in disease-specific networks are enr... 2012 · 81 cites
- An integrative analysis reveals functional targets of GATA6 tran... 2013 · 81 cites
- Aberrant DNA methylation of WNT pathway genes in the development... 2016 · 81 cites
- Ranking metrics in gene set enrichment analysis: do they matter? 2017 · 80 cites
- The lncRNA ZFAS1 regulates lipogenesis in colorectal cancer by b... 2021 · 76 cites
56 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently
Scientific quality
Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.