Corpus 1,280 assessed · 1,181 scored · 646 reproduced ≥75 · 170 flagged ·∅ 74/100
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GSE99823

GEO first seen 2017

Transcriptome-wide characterization of human cytomegalovirus in natural infection and experimental latency

Organism
Human betaherpesvirus 5
Samples
49
Type
Expression profiling by high...
Submitted
2017-06-08

Abstract: The transcriptional program associated with herpesvirus latency and the viral genes regulating entry into and exit from latency are poorly understood and controversial. Here, we developed and validated a targeted enrichment platform and conducted large-scale transcriptome analyses of human cytomegalovirus (HCMV) infection. We used both an experimental hematopoietic cell model of latency, and cells from naturally infected, healthy human subjects (clinical) to define the breadth of viral...

Provenance — who produced it, who reused it

Linked to 2 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
Shu ChengKatie CavinessJason BuehlerMegan SmitheyJanko Nikolich-ZugichFelicia Goodrum
Reused by

Deep data QC

metadata only · no data-level QC for this type

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained

Data type / assay
bulk-RNA-seq
Organism
Human betaherpesvirus 5
Instrument
Illumina HiSeq 2500
Platform
ILLUMINA
Read type
short-read
Files available
FASTQ (raw reads)
N numbers (samples, groups)
49 / 49 runs
Completeness
100%
Metrics (value · how obtained)
checksum ok yes reported
total bases 165572064341 reported
total reads 803801753 reported
supplementary file types TXT reported
QC cost 16 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently