Corpus 1,272 assessed · 1,173 scored · 643 reproduced ≥75 · 168 flagged ·∅ 74.1/100
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PRJEB42372

BioProject first seen 2021

Provenance — who produced it, who reused it

Linked to 1 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Reused by

1 further paper cites this accession but reuse could not be confirmed.

Deep data QC

99/100 · A

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured

What this means
claude:haiku

This Illumina HiSeq 4000 whole-exome sequencing dataset from Homo sapiens uses targeted capture to profile 910 million reads and 64 billion bases with excellent quality (98% Q20, 92.5% Q30), enabling high-sensitivity variant calling across coding regions. The elevated 59.9% GC (above typical exome ~50%) suggests either GC-rich targets or capture-kit bias; researchers should verify capture method and any GC-correction applied. The dataset is suitable for disease-gene discovery and clinical-exome interpretation.

Data type / assay
WES
Organism
Homo sapiens
Instrument
Illumina HiSeq 4000
Platform
ILLUMINA
Read type
short-read
Files available
FASTQ (raw reads), BAM/CRAM (aligned)
N numbers (samples, groups)
50 runs
Metrics (value · how obtained)
checksum ok yes reported
total bases 64076391567 reported
total reads 910593791 reported
n content pct 0 measured
pct q20 bases 98 measured
pct q30 bases 92.5 measured
gc content pct 59.9 measured
mean read length 61.5 measured
mean base quality 38.2 measured
adapter content pct 0.35 measured
duplication rate pct 13.03 measured
mean target coverage 1033.5 extrapolated
How this grade was computed
Weighted mean of 4 scored metric(s) → 99/100

The A grade is a transparent weighted average. Each metric below scored from 0–100% against the published WES thresholds, weighted by its importance; nothing is hidden or subjective.

mean target coverage 1033.5 extrapolated ×1.2 100%
pct q30 bases 92.5 measured ×1 100%
duplication rate pct 13.03 measured ×0.5 97%
adapter content pct 0.35 measured ×0.4 100%
QC cost 28 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0