Corpus 1,272 assessed · 1,173 scored · 643 reproduced ≥75 · 168 flagged ·∅ 74.1/100
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PRJNA241071

BioProject first seen 2014

Provenance — who produced it, who reused it

Linked to 1 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Reused by

1 further paper cites this accession but reuse could not be confirmed.

Deep data QC

100/100 · A

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured

What this means
claude:haiku

Whole-exome sequencing (WXS) of Homo sapiens via HiSeq 2000 with ~797M reads capturing ~165 Gb total bases, representing deep exome coverage. This dataset supports rare disease variant discovery, loss-of-function mutation identification, and population-level allele frequency estimation across protein-coding regions. The large number of reads and 92.4% Q30 bases enable confident calling of single-nucleotide and small indel variants in the exome.

Data type / assay
WES
Organism
Homo sapiens
Instrument
Illumina HiSeq 2000
Platform
ILLUMINA
Read type
short-read
Files available
FASTQ (raw reads)
N numbers (samples, groups)
16 runs
Metrics (value · how obtained)
checksum ok yes reported
total bases 165362173384 reported
total reads 796800839 reported
n content pct 0.005 measured
pct q20 bases 97.2 measured
pct q30 bases 92.4 measured
gc content pct 43.4 measured
mean read length 100 measured
mean base quality 36.1 measured
adapter content pct 0.02 measured
duplication rate pct 1.04 measured
mean target coverage 2667.1 extrapolated
How this grade was computed
Weighted mean of 4 scored metric(s) → 100/100

The A grade is a transparent weighted average. Each metric below scored from 0–100% against the published WES thresholds, weighted by its importance; nothing is hidden or subjective.

mean target coverage 2667.1 extrapolated ×1.2 100%
pct q30 bases 92.4 measured ×1 100%
duplication rate pct 1.04 measured ×0.5 100%
adapter content pct 0.02 measured ×0.4 100%
QC cost 36 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0