Corpus 1,272 assessed · 1,173 scored · 643 reproduced ≥75 · 168 flagged ·∅ 74.1/100
← Dataset search

SRP046046

ENA first seen 2016

Provenance — who produced it, who reused it

Linked to 3 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Reused by

3 further papers cite this accession but reuse could not be confirmed.

Deep data QC

83/100 · B

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured

What this means
claude:opus

This is a human small-RNA (miRNA-Seq) dataset, and overall it earns a solid B (83/100) that is trustworthy rather than provisional, since the contributing metrics were all directly measured (evidence_strength=1) rather than extrapolated. The grade is held up by excellent base-level quality — 90.3% of bases at Q30, a mean base quality of 35.1, and 0% adapter contamination — meaning the reads themselves are clean, accurately called, and ready to map without aggressive trimming. The one metric pulling the score down is a 92.06% duplication rate, which scored 0; in most assays that would signal a low-complexity library, but for miRNA-Seq extreme duplication is largely expected and biologically driven, because mature miRNAs are short, few in number, and very highly expressed, so identical reads are the norm rather than evidence of PCR artifact. For reuse the practical verdict is positive: treat the high duplication as a property of the assay rather than a defect, and the clean, high-quality, adapter-free reads make this dataset reliable for miRNA quantification and differential-expression analysis.

Data type / assay
bulk-RNA-seq
Organism
Homo sapiens
Instrument
Illumina HiSeq 2000
Platform
ILLUMINA
N numbers (samples, groups)
12 runs
Metrics (value · how obtained)
checksum ok yes reported
total bases 9270399719 reported
total reads 92241950 reported
n content pct 0.011 measured
pct q20 bases 91.7 measured
pct q30 bases 90.3 measured
gc content pct 44.5 measured
mean read length 100 measured
mean base quality 35.1 measured
adapter content pct 0 measured
duplication rate pct 92.06 measured
How this grade was computed
Weighted mean of 4 scored metric(s) → 83/100

The B grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.

pct q30 bases 90.3 measured ×1 100%
mean base quality 35.1 measured ×0.6 100%
adapter content pct 0 measured ×0.4 100%
duplication rate pct 92.06 measured ×0.4 0%
QC cost 6 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0

Scientific quality

Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.

1 studies use it