Corpus 1,273 assessed · 1,174 scored · 643 reproduced ≥75 · 169 flagged ·∅ 74.1/100
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SRR553575

ENA first seen 2018

Provenance — who produced it, who reused it

Linked to 1 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Reused by

1 further paper cites this accession but reuse could not be confirmed.

Deep data QC

75/100 · C

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured

What this means
claude:opus

Bulk RNA-seq from human cells on the older Illumina Genome Analyzer IIx, this dataset earns a middling C (75/100) on fully measured QC metrics, so the reading is reliable rather than provisional. Base quality is genuinely strong — 90.8% of bases at Q30 and a mean base quality of 32.1, with effectively zero adapter and N content — meaning the underlying reads are clean and trustworthy for alignment. The grade is dragged down almost entirely by a 94.08% duplication rate, which scored 0 and is the dominant concern: such extreme duplication points to limited library complexity (likely heavy PCR amplification from low input), so the effective number of independent molecules is far smaller than the 25M reads suggest, which inflates expression estimates and weakens quantification. Practically, this data is reusable for qualitative or exploratory RNA-seq work but should be treated cautiously for differential-expression or low-abundance transcript analysis, and the very short 37 bp reads further limit multi-mapping and isoform resolution.

Data type / assay
bulk-RNA-seq
Organism
Homo sapiens
Instrument
Illumina Genome Analyzer IIx
Platform
ILLUMINA
N numbers (samples, groups)
1 runs
Metrics (value · how obtained)
checksum ok yes reported
total bases 931416614 reported
total reads 25173422 reported
n content pct 0.01 measured
pct q20 bases 95.2 measured
pct q30 bases 90.8 measured
gc content pct 47.2 measured
mean read length 37 measured
mean base quality 32.1 measured
adapter content pct 0 measured
duplication rate pct 94.08 measured
How this grade was computed
Weighted mean of 4 scored metric(s) → 75/100

The C grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.

pct q30 bases 90.8 measured ×1 100%
mean base quality 32.1 measured ×0.6 68%
adapter content pct 0 measured ×0.4 100%
duplication rate pct 94.08 measured ×0.4 0%
QC cost 16 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0

Scientific quality

Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.

1 studies use it 1 reproduced mean score 89