Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Genomic and epigenetic instability in colorectal cancer pathogenesis.
PMID 18773902 · PMC2866182 · Gastroenterology · 2008 · 8 claims · 7 setups
Genomic instability (CIN or MSI) is a key early molecular step in colorectal tumorigenesis that may initiate rather than merely accompany the adenoma-carcinoma sequence
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PAF15-PCNA exhaustion governs the strand-specific control of DNA replication.
PMID 41606318 · PMC12979207 · Nature · 2026 · 8 claims · 8 setups
Excessive origin firing saturates chromatin-bound PCNA, restricting further PCNA loading and lagging-strand synthesis when checkpoint control is lost.