Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 6

System / cell line: enriched ✕ Assay: affinity ✕ Clear

Improved methods for the enrichment and analysis of glycated peptides.

PMID 18989935 · PMC2752342 · Analytical chemistry · 2008 · 7 claims · 4 setups

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Replacing off-line desalting with an online 50 mM NH4OAc wash (10 min) of boronate-bound glycated proteins improves the enrichment workflow while minimizing sample loss

glucose-glycated tryptic glycated lc-ms boronate lc-etd-ms database
Technical Brief: a novel strategy for enrichment of trabecular meshwork protease proteome.

PMID 18490959 · PMC2386506 · Molecular vision · 2008 · 7 claims · 6 setups

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A novel affinity-enrichment strategy using UV cross-linked protease inhibitor peptides on Protein A/G columns improves capture of the TM protease proteome compared to SDS-PAGE fractionation alone

cytosolic affinity-eluted porcine affinity-enriched affinity western sds-page
Post-translational modifications of histones H3 and H4 associated with the histone methyltransferases Suv39h1 and G9a.

PMID 18096052 · PMC2246272 · Genome biology · 2007 · 6 claims · 4 setups

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Suv39h1 and G9a associate with previously reported methylation states (Suv39h1 with H3K9me3; G9a with H3K9me/me2)

crude hela-suv39h1 suv39h1 normal propionylation-based double maldi-tof
Protein interaction networks by proteome peptide scanning.

PMID 14737190 · PMC314469 · PLoS biology · 2004 · 8 claims · 7 setups

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WISE (combining phage display-derived relaxed consensus patterns with SPOT peptide synthesis arrays) can identify proteome-wide binding partners of a peptide-recognition domain

cerevisiae synthetic yeast tap-tagged phage spot surface
High-throughput sequencing SELEX for the determination of DNA-binding protein specificities in vitro.

PMID 35776646 · PMC9243297 · STAR protocols · 2022 · 8 claims · 8 setups

Has reproduction · 65

HT-SELEX enables unbiased, in vitro determination of preferred DNA target motifs for DNA-binding proteins by iterative selection and PCR amplification of bound oligonucleotides

synthetic pcr-generated selex histidine-tagged pcr polyacrylamide spectrophotometry
Exploring the role and mechanism of Astragalus membranaceus and radix paeoniae rubra in idiopathic pulmonary fibrosis through network pharmacology and experimental validation.

PMID 37666859 · PMC10477296 · Scientific reports · 2023 · 8 claims · 8 setups

Has reproduction · 20

AM and RPR (Huangqi-Chishao decoction) alleviate bleomycin-induced pathological lung fibrotic damage in rats

ipf common key rats microarray network protein-protein

Experiments

Improved methods for the enrichment and analysis of glycated peptides.

Technical Brief: a novel strategy for enrichment of trabecular meshwork protease proteome.

Post-translational modifications of histones H3 and H4 associated with the histone methyltransferases Suv39h1 and G9a.

Protein interaction networks by proteome peptide scanning.

High-throughput sequencing SELEX for the determination of DNA-binding protein specificities in vitro.

Exploring the role and mechanism of Astragalus membranaceus and radix paeoniae rubra in idiopathic pulmonary fibrosis through network pharmacology and experimental validation.