Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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SIGMA: a system for integrative genomic microarray analysis of cancer genomes.
PMID 17192189 · PMC1764892 · BMC genomics · 2006 · 7 claims · 6 setups
SIGMA is a user-friendly, web-based Java application for visualization and integrative analysis of array CGH data across multiple platforms.
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New center a stroke of gene-ius.
PMID 11171539 · PMC1242068 · Environmental health perspectives · 2001 · 8 claims · 4 setups
Exposure to alkylating agents evokes at least three-fold expression changes in about one-third of the yeast genome (~2,000 genes), far beyond DNA repair genes alone
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A simple and robust method for connecting small-molecule drugs using gene-expression signatures.
PMID 18518950 · PMC2464610 · BMC bioinformatics · 2008 · 8 claims · 4 setups
A new method for building reference gene-expression profiles and scoring/testing connections improves on the original Connectivity Map by enabling statistical significance testing of connections.
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Has reproduction · 96
Deep learning based protocol to construct an immune-related gene network of host-pathogen interactions in plants.
PMID 36525344 · PMC9791427 · STAR protocols · 2023 · 6 claims · 6 setups
A deep-learning protocol (DLNet) ranks genes by their contribution to classifying treatment versus control expression data, identifying genes involved in host defense against pathogens.
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Are gene expression microarray analyses reliable? A review of studies of retinoic acid responsive genes.
PMID 15626329 · PMC5171945 · Genomics, proteomics & bioinformatics · 2003 · 6 claims · 8 setups
Published microarray studies aiming to identify RA-responsive genes show substantial, often contradictory, differences in results across research groups.
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Chromosome-wide identification of novel imprinted genes using microarrays and uniparental disomies.
PMID 16855283 · PMC1524921 · Nucleic acids research · 2006 · 8 claims · 5 setups
Four novel brain-specific paternally expressed transcripts (BB077283, BM117114, AK080843, AV328498) were identified and validated on proximal Chr 7.
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Has reproduction · 82
SMAGEXP: a galaxy tool suite for transcriptomics data meta-analysis.
PMID 30698691 · PMC6354025 · GigaScience · 2019 · 8 claims · 5 setups
SMAGEXP integrates the metaMA and metaRNASeq R packages into Galaxy to provide a unified tool suite for transcriptomics meta-analysis.
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6th annual meeting of the Complex Trait Consortium.
PMID 17906895 · PMC2042027 · Mammalian genome : official journal of the International Mammalian Genome Society · 2007 · 8 claims · 7 setups
The NIEHS Perlegen/resequencing project has generated over 8.5 million SNPs from 15 inbred mouse strains but shows a high false-negative discovery rate, with an estimated 45 million SNPs actually present.
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Has reproduction · 62
A curated collection of transcriptome datasets to investigate the molecular mechanisms of immunoglobulin E-mediated atopic diseases.
PMID 31290545 · PMC6616200 · Database : the journal of biological databases and curation · 2019 · 5 claims · 8 setups
A curated collection of 33 GEO transcriptome datasets relevant to IgE-mediated atopic diseases (allergies to primary immunodeficiencies) was assembled, encompassing 1860 transcriptome profiles.
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Has reproduction · 71
Artificial intelligence-guided discovery of gastric cancer continuum.
PMID 36692601 · PMC9871434 · Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2023 · 8 claims · 8 setups
A Boolean implication network built from GSE66229 yields a GC-BoNE gene signature (Boolean paths C#11-2-4-14 and C#7-13-14) that classifies tumor vs normal/adjacent-normal gastric samples