Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 76
Estimation of peptide elongation times from ribosome profiling spectra.
PMID 33885812 · PMC8136808 · Nucleic acids research · 2021 · 8 claims · 3 setups
A maximum-likelihood model that separates context-dependent bias factors from elongation-time factors enables bias-corrected estimation of peptide elongation times at single-codon resolution from Ribo-Seq spectra.
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Has reproduction · 98
A data-driven estimation of the ribosome drop-off rate in S. cerevisiae reveals a correlation with the genes length.
PMID 38638702 · PMC11025885 · NAR genomics and bioinformatics · 2024 · 8 claims · 7 setups
Ribosome drop-off events occur at a significant rate in S. cerevisiae cultured in standard conditions
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Has reproduction · 74
Disome-seq reveals widespread ribosome collisions that promote cotranslational protein folding.
PMID 33402206 · PMC7784341 · Genome biology · 2021 · 8 claims · 8 setups
Disome-seq sequences mRNA fragments protected by two stacked (collided) ribosomes, detecting ribosome collisions at codon resolution.