Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 506

Assay: amplification ✕ Clear

Expanding CEP290 mutational spectrum in ciliopathies.

PMID 19764032 · PMC4340070 · American journal of medical genetics. Part A · 2009 · 7 claims · 4 setups

Full-text index only

A large heterozygous genomic deletion spanning the CEP290 C-terminus (exons 42-54) was identified in a JSRD-COR patient previously known to carry only one CEP290 point mutation.

peripheral genomic quantitative cdna pcr
A genome-wide screen for copy number alterations in Aicardi syndrome.

PMID 19760649 · PMC3640635 · American journal of medical genetics. Part A · 2009 · 7 claims · 4 setups

Full-text index only

Aicardi syndrome is thought to result from heterozygous defects in an essential X-linked gene, or from a sex-limited autosomal gene defect, due to its occurrence almost exclusively in females and in 47,XXY males.

genomic subject array quantitative fluorescence
Mutations that are a common cause of Leber congenital amaurosis in northern America are rare in southern India.

PMID 19753312 · PMC2742639 · Molecular vision · 2009 · 7 claims · 4 setups

Full-text index only

Mutations responsible for over 30% of LCA cases in northern America were found in only 2.6% of LCA cases in a southern Indian cohort.

unrelated lca genomic allele-specific bidirectional electroretinogram
Helicobacter Pylori's plasticity zones are novel transposable elements.

PMID 19727398 · PMC2731543 · PloS one · 2009 · 8 claims · 8 setups

Full-text index only

Plasticity zones are a novel class of transposable elements (named TnPZs), flanked by direct repeats of 5'AAGAATG and inserted at multiple discrete chromosomal sites

pylori shimaa model mammalian pcr-based genome pcr
Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population.

PMID 19671850 · PMC2865649 · Clinical cancer research : an official journal of the American Association for Cancer Research · 2009 · 8 claims · 6 setups

Full-text index only

20 of 358 (5.6%) lung adenocarcinomas from Western institutions harbored ALK rearrangements

formalin-fixed lung sections poorly fluorescent immunohistochemistry mutational
Genomic and mutational profiling to assess clonal relationships between multiple non-small cell lung cancers.

PMID 19671847 · PMC2892178 · Clinical cancer research : an official journal of the American Association for Cancer Research · 2009 · 8 claims · 5 setups

Full-text index only

Genomic profiling by aCGH can distinguish clonal tumors from independent primaries with high confidence by identifying matching versus non-matching regions of allelic gain/loss.

fresh-frozen same banked resected array mutational pcr
Recurring mutations found by sequencing an acute myeloid leukemia genome.

PMID 19657110 · PMC3201812 · The New England journal of medicine · 2009 · 8 claims · 8 setups

Full-text index only

Deep paired tumor/normal whole-genome sequencing of a cytogenetically normal AML-M1 genome identified 12 somatic coding (tier 1) mutations and 52 somatic tier 2 (conserved/regulatory) mutations.

aml-m1 tumor bone additional whole-genome snp gene-expression
Sequence variation of PfEMP1-DBLalpha in association with rosette formation in Plasmodium falciparum isolates causing severe and uncomplicated malaria.

PMID 19650937 · PMC3224928 · Malaria journal · 2009 · 8 claims · 5 setups

Full-text index only

Sequence group 1 (mainly from uncomplicated malaria) is significantly different in distribution from sequence group 3 (mainly from severe malaria)

falciparum falciparum-infected pcr-amplified non-identical static rosette rt-pcr
MrHAMER yields highly accurate single molecule viral sequences enabling analysis of intra-host evolution.

PMID 33849057 · PMC8266615 · Nucleic acids research · 2021 · 8 claims · 7 setups

Full-text index only

MrHAMER yields >1000s of viral genomes per sample at 99.9% accuracy

psg3.1 transcribed double-stranded mrhamer transcription reverse mrhamer
Microbial community dynamics over large spatial and environmental gradients in a subtropical ocean basin.

PMID 41568968 · PMC12915303 · Applied and environmental microbiology · 2026 · 8 claims · 7 setups

Full-text index only

Cluster analysis of 18S (and similarly 16S) community data revealed three clusters corresponding to depth zones: photic zone, deep chlorophyll maximum (DCM), and aphotic zone

seawater sterivex-filtered extracted log-transformed metabarcoding hydrographic extraction
Expression of ultralong complementarity determining region 3 and development of IgM and IgG B cell receptor repertoires in Holstein heifer calves.

PMID 41588676 · PMC12857222 · ImmunoHorizons · 2026 · 7 claims · 6 setups

Full-text index only

The percentage of productive IgM sequences with ultralong CDR3 significantly increases between day 90 and ~day 285 of life

igm+ igg+ bovine sorted long-read magnetic-activated rt-pcr
Parasitic connections: a patescibacterial epibiont, its methylotrophic gammaproteobacterial host, and their phages.

PMID 41805398 · PMC13059738 · mBio · 2026 · 8 claims · 7 setups

Full-text index only

Strigamonas methylophilicida sp. nov. is a new patescibacterial genus and species within the family Absconditicoccaceae

freshwater fixed rsa individual phase transmission fluorescence-activated
Single-cell sequencing reveals unexpected genetic diversity among Bodo spp. flagellates and their bacterial endosymbionts.

PMID 41848149 · PMC12999062 · Microbial genomics · 2026 · 8 claims · 8 setups

Full-text index only

Seven single-cell genomes assembled from uncultured environmental Bodo cells represent three potentially novel Bodo species

uncultured environmental single-cell bodo single-cell fluorescence-activated whole-genome
Analysis of the p53 gene by PCR-SSCP in ten cases of Wilms' tumor.

PMID 10772697 · PMC11166235 · Sao Paulo medical journal = Revista paulista de medicina · 2000 · 7 claims · 3 setups

Full-text index only

Point mutations of the p53 gene (exons 5-9) were not detected in any of the 10 Wilms' tumor samples studied

extracted pcr-amplified pcr pcr pcr-sscp automated
Colorectal cancer genomics: evidence for multiple genotypes which influence survival.

PMID 11720434 · PMC2363933 · British journal of cancer · 2001 · 6 claims · 3 setups

Full-text index only

Genetic grade (total number of CGH-detected gains+losses) varies greatly among Dukes' C CRC tumours and shows a multimodal (non-normal) distribution

dukes colorectal comparative kaplan-meier
Detection of an Ala601Thr mutation of plasminogen gene in 3 out of 36 Korean patients with deep vein thrombosis.

PMID 12692411 · PMC3055032 · Journal of Korean medical science · 2003 · 7 claims · 3 setups

Full-text index only

Dysplasminogenemia was identified in 3 of 36 (8.3%) unrelated Korean DVT patients.

plasma genomic amidolytic immunoturbidimetric pcr
PrimerSeq: Design and visualization of RT-PCR primers for alternative splicing using RNA-seq data.

PMID 24747190 · PMC4411361 · Genomics, proteomics & bioinformatics · 2014 · 8 claims · 3 setups

Has reproduction · 90

PrimerSeq is a user-friendly stand-alone software with a GUI for systematic design and visualization of RT-PCR primers for alternative splicing analysis using user-provided RNA-seq data.

heart genome rna-seq rt-pcr
SiDCoN: a tool to aid scoring of DNA copy number changes in SNP chip data.

PMID 17971856 · PMC2034603 · PloS one · 2007 · 8 claims · 3 setups

Full-text index only

SiDCoN is a spreadsheet-based application that simulates Ballele and logR plots for all known types of DNA copy number change, with or without stromal contamination, for up to 5000 SNP data points and up to 3 combined aberrations

sidcon real mixtures snp re-analysis
Functional copy-number alterations in cancer.

PMID 18784837 · PMC2527508 · PloS one · 2008 · 8 claims · 3 setups

Full-text index only

RAE is a comprehensive computational framework that robustly maps chromosomal alterations in tumor samples and statistically assesses their functional importance in cancer.

pleomorphic hapmap large snp computational
High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors: four cases of homozygous deletions of the CDKN2A gene.

PMID 18664255 · PMC2527340 · BMC genomics · 2008 · 8 claims · 3 setups

Full-text index only

Affymetrix 50K/250K SNP arrays with CNAG3.0 software provide high-resolution (10-12kb) copy number and allele-specific information suitable for characterizing chromosomal rearrangements in neuroblastoma tumors

neuroblastoma snp multiplex

Experiments

Expanding CEP290 mutational spectrum in ciliopathies.

A genome-wide screen for copy number alterations in Aicardi syndrome.

Mutations that are a common cause of Leber congenital amaurosis in northern America are rare in southern India.

Helicobacter Pylori's plasticity zones are novel transposable elements.

Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population.

Genomic and mutational profiling to assess clonal relationships between multiple non-small cell lung cancers.

Recurring mutations found by sequencing an acute myeloid leukemia genome.

Sequence variation of PfEMP1-DBLalpha in association with rosette formation in Plasmodium falciparum isolates causing severe and uncomplicated malaria.

MrHAMER yields highly accurate single molecule viral sequences enabling analysis of intra-host evolution.

Microbial community dynamics over large spatial and environmental gradients in a subtropical ocean basin.

Expression of ultralong complementarity determining region 3 and development of IgM and IgG B cell receptor repertoires in Holstein heifer calves.

Parasitic connections: a patescibacterial epibiont, its methylotrophic gammaproteobacterial host, and their phages.

Single-cell sequencing reveals unexpected genetic diversity among Bodo spp. flagellates and their bacterial endosymbionts.

Analysis of the p53 gene by PCR-SSCP in ten cases of Wilms' tumor.

Colorectal cancer genomics: evidence for multiple genotypes which influence survival.

Detection of an Ala601Thr mutation of plasminogen gene in 3 out of 36 Korean patients with deep vein thrombosis.

PrimerSeq: Design and visualization of RT-PCR primers for alternative splicing using RNA-seq data.

SiDCoN: a tool to aid scoring of DNA copy number changes in SNP chip data.

Functional copy-number alterations in cancer.

High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors: four cases of homozygous deletions of the CDKN2A gene.